Tag: Nutrition

The function of the kidneys is to purify and metabolize the toxic and old waste substances in our blood, and to excrete them through urination. The decline of kidney function can lead to uremia due to poor blood metabolism. After entering the human body, small peptides will participate in the process of kidney cell regeneration, growth, repair, and activation. Providing the raw materials needed for cell production can help kidney patients improve their purification and metabolism capabilities. The effects of small molecules are: 1. Repair deleted cells and improve cell metabolism; 2. Improve immunity and maintain resistance; 3. Enhance liver function and enhance human waste metabolism.

People with kidney problems should control their protein intake. Protein needs to be decomposed by various enzymes and enzymes in the body before it can be used by the body. Decomposing it will excrete nitrogen waste and increase the burden on the kidneys. It is recommended that people only eat 0.8 grams of protein per kilogram of body weight. ; But the protein unit is different from the small molecule peptide, and the small molecule peptide itself has been decomposed in vitro, and the human body can directly absorb 100% without second digestion. Therefore, it is safe for patients with kidney disease. It is recommended to eat three meals before For example, supplementing small peptides on an empty stomach can help to obtain health from cells, tissues and kidneys.

People with kidney problems should also control their daily diet. They should have less salt, less oil and sugar, and should not take too much vitamin C. Many people are accustomed to using vitamin C to enhance immunity and prevent themselves from contracting pneumonia or flu. However, they eat too much vitamin C. It will increase the risk of kidney stones. It is recommended that 1000 mg per day is the upper limit.

It is also important to drink enough water. From the color of urination, light yellow means that the water volume is just right. Remember not to restrict the daily water volume strictly because the kidney function declines and the water processing capacity is reduced. Sufficient water can help activate the cells. Accelerate metabolism and detoxification, so in addition to supplementing small molecule peptides, it is also necessary to supplement water.

Finally, the current medical research on cell therapy is expected to repair kidney function, and hope that it will succeed soon, please refer to the following link -> http://health.udn.com/health/story/5999/3376082。

Small molecule peptide supplements are available in our store, please contact us for enquiries -> click here.

The characteristics of aging include DNA damage, changes in the epigenome, loss of healthy protein maintenance ability, stem cell failure and the production of inflammatory molecules… etc. The key to anti-aging is to activate vitality genes, which are both the cause and reversal of aging. The key to aging. NAD+ is the substrate of the DNA repair protein PARP1 and the activator of the longevity gene SIRT1, which plays a key physiological function. However, during the aging process, the content of NAD+ will rapidly decrease, which directly leads to a significant decrease in the activity of SIRT1, which affects mitochondrial function, and reduces the power of the “cell’s power plant”, leading to aging. This explains the relationship between aging and NAD+. And many scientific research experiments have consistently confirmed that maintaining sufficient NAD+ in cells and maintaining the energy of the “cell power plant” mitochondria is the key to inhibiting aging.

As we age, our body’s NAD+ does not work well: when we are 50, the amount of NAD in our body is half of what it was when we were 20, so the cells in our body will forget what they should be doing. Aging begins here. Aging is also accompanied by various diseases. Aging is a disease and it can be cured. As long as aging is treated, the disease can be combated!

NAD+ is the central molecule in the human body, which controls the activity and amount of mitochondria and provides 95% of the body’s energy. At the same time, it can repair damaged DNA in cells and activate Sirtuins longevity genes. But NAD+ declines with age, leading to aging. NMN is the precursor of NAD+. Professor David Sinclair found that supplementing with NMN can increase the level of NAD+ in the body and achieve the effect of reversing aging!

The mechanism of rejuvenation of NMN is: NMN -> convert to NAD+ -> start Sirtuins1~7 longevity gene + activate mitochondria + repair cell DNA + stem cell activation + telomere length maintenance + autophagy increase + immune regulation increase + infertility Reduce -> Healthy and Longevity + Becoming Young + Decrease the Speed ​​of Aging + Restore Youth

NMN four manufacturing methods

(1) Chemical synthesis:

Non-biological natural synthesis method, through trityl ribose or acetyl ribose as starting materials, through bromine substitution, nicotinamide substitution, deacetylation, debenzylation, phosphorylation and other reaction steps Get NMN.

(2) Enzyme synthesis:

Using nicotinamide, adenosine triphosphate, ribose, etc. as starting materials, using various biological enzymes and NAMPT for catalysis to obtain NMN, the reaction conversion rate can reach 80% to 100%. Among them, the Nobel Prize-winning enzyme directed evolution technology, SPT synthetase technology, and RNA biocatalysis technology are more advanced technologies.

(3) Lactic acid bacteria fermentation:

Fermentation with lactic acid bacteria is also one of the manufacturing methods of NMN. For example, in April 2021, Shizuoka University in Japan revealed the method of producing NMN by lactic acid bacteria in the journal Scientific Reports. Find out 3 kinds of anaerobic lactic acid bacteria. During the fermentation process, adding fructose will cause NMN and NR to accumulate in the cells.

(4) Escherichia coli gene engineering:

NMN can also be obtained through Escherichia coli microbial technology. For example, in 2018, the University of Bucharest in Romania stated in the Journal of Scientific Reports that the method of purifying NMN from bacteria was described. Also in May 2021, Kobe University in Japan published a paper in the Journal of Metabolic Engineering, titled: Design of selective production of NMN from glucose and NAM (nicotinamide). They used E. coli to develop a whole-cell biocatalyst that can efficiently produce NMN from cheap raw materials glucose and NAM (nicotinamide).

Among the NMN products currently on the market in 2022, the NMN manufactured by enzymatic synthesis has the most stable quality, the highest purity and activity, and the best bioconversion rate!

The functions of NMN are as follows:

• NMN reverses muscle aging and prevents radiation.​​
• NMN reverses vascular aging, regenerates blood vessels, and has a significant protective effect on cerebral blood vessels.​​
• NMN stabilizes telomeres, enhances gene repair, and improves basic metabolism ​​
• NMN hangover and protect liver, ​​
• NMN improves depressive behavior
• NMN​​​Improve sex hormone
• NMN improves sexual function, improves kidney function, restores energy and enhances physical strength.
• NMN boosts immunity, fights viruses and cancer

Reference: https://www.victornmn0520.com/%E7%A5%9E%E5%A5%87%E7%9A%84nmn

Peptide (English: peptide, from the Greek word for “digest”) is a naturally occurring small biological molecule, a substance between amino acid and protein. In recent years, various peptide products have sprung up in an endless stream. Under the widespread publicity in the market, more and more consumers have learned about peptides. Some people say that it is more powerful than the elixir and can cure all diseases; others say that there is life if there is peptide, and life ends if there is no peptide.

First of all, we have to understand that peptides are neither health products nor medicines, but a kind of functional food of cells that are superior to health products and medicines. In other words, it is cellular food, as safe as eating, without any side effect. Therefore, there is no problem of overdose of peptide supplementation, unlike the problem of taking too much medicine.

Secondly, peptides are very important to the human body and control the physiological functions of the human body. Peptides are an endogenous substance in the human body. Every activity of our body, including every breath and every heartbeat, is determined by peptides. If our body leaves the peptide, these activities will be gone. In addition, all our physiological functions are low, disorder, all disease states and sub-health states are caused by peptide deficiency.

Furthermore, the functions of all nutritional products, health foods and medicines are incomplete, and only peptides have the most comprehensive functions. As the famous American scientist Dr. Yu Klin pointed out: “Peptides are used to treat almost any disease. There is no medicine to compare with them.” Peptides also have carrier functions, which can promote the absorption of health care products and medicines and deliver them to urgent needs. Where to go, this is the advantage of peptides.

Since amino acids have the smallest molecules and proteins the largest, short chains of amino acid monomers connected by peptide bonds. When the carboxyl group of one amino acid reacts with the amino group of another amino acid, the covalent chemical bond is formed. Dipeptides (referred to as dipeptides) are protein fragments composed of two amino acids. Two or more amino acids are dehydrated and condensed to form several peptide bonds to form a peptide. Multiple peptides are formed by multi-fold folding. A protein molecule.

Amino acids make up proteins through peptide bonds. The hydrolysis of proteins into single molecules of amino acids is not high-tech. Decomposition into small peptides is not high-tech. Peptides can be hydrolyzed from dietary protein (dietary protein) through chemical methods or can be obtained artificially. . It is composed of the polymerization of two or more amino acids, which is very important in the regulation of cell physiology and metabolic functions. Most of the peptides are unstable, so they should be kept away from moisture for long-term storage and kept below 4°C.

Active peptides are closely related to nutrition, hormones, enzyme inhibition, immunity regulation, antibacterial, antiviral [2], and antioxidant. Peptides are small molecules, scavengers, repairers, and porters. Peptides can provide nutrients and energy to cells, inhibit, repair, activate, and promote normal cell work and metabolism. Peptides are not medicines, nor can they replace medicines, but sometimes they can solve problems that medicines can’t solve. They can enhance one’s own immunity and change the sub-health state of the human body. The scope of application of peptides:

1. Peptide products cover comprehensive nutrition and health care — Nutritional health products contain a certain amount of functional ingredients and have specific effects for a certain aspect. Peptides are sourced in the human body, which can regulate various parts of the human body, so as to achieve the balance of the human body.

2. Peptide products are suitable for all people — Nutritional health products have specific effects, so there are generally specific people who take them. Peptides are medical-grade foods that can synthesize various proteins in the human body and are substances that everyone needs to supplement.

3. There is no excessive restriction on peptide products — Excessive consumption of nutrient health products can lead to too much of a certain nutrient in the body, resulting in an imbalance in the total proportion of the human body, which is not conducive to health. Peptides are substances that exist in the human body. Even if they are taken too much, the body will accelerate the elimination of them, but it will only cause the waste of small molecule peptides, and there is no other harm.

The health effects of peptides on the human body:

1. Inhibition-inhibit cell degeneration and enhance human immunity.
2. Activation-activate cell activity, effectively remove free radicals harmful to the human body.
3. Repair-repair human degenerated cells and improve cell metabolism.
4. Promote-promote and maintain normal cell metabolism.